The result is my Facebook status updates are mostly about broader life events while my Twitter updates are primarily work related.
It's a bit more work, but I find that my friends and family members are now actually reading my Facebook updates (and commenting on them) rather than dismissing them as "more of Alan's work-related geekery." And since I finally figured out how to link Facebook to Delicious, I can share articles I like without overwhelming people, since Facebook posts them as a list. (A trick I learned from Noah Brier, who I often joke serves as my personal online librarian.)
Not sure if this is a harbinger of things to come or my own personal tic, but curious to hear how others are bridging the gap.